It was all installed off the CD. I did notice that when the disc was left out and the desktop icon was clicked, the message about not finding the CD came up right away. However, when the icon was clicked with disc, that loading box was there for fifteen or so seconds while the cd drive was being accessed. Then, the same error message would pop up. So, how could it not find the CD when it seemed to be reading the program right off the very disc it claims does not exist? Makes me think that either Vista with it's slightly different way of looking at directory structure is misinterpreting how to find this security key or V15 disc has a vital file missing from the place the program is seeking it out at.
Now, unless there's a way to include switches to correct this spot to find the file at inside the desktop icon's properties, I see nothing that can be done to fix the error, as the exe file is coming off of a read only source.